Bacteriological Profile of Surgical Site Infection: A Descriptive Study at Deido District Hospital in Douala, Cameroon

Faustin Atemkeng Tsatedem *

Faculty of Medecine and Pharmaceutical Sciences, University of Dschang, Hospital Practionner, Cameroon.

Fondop J.

Faculty of Medecine and Pharmaceutical Sciences, University of Dschang, Hospital Practionner, Cameroon.

Bayol A. D.

Univeristy of Bamenda, Cameroon.

J. H. Donfack

Faculty of Medecine and Pharmaceutical Sciences, University of Dschang, Hospital Practionner, Cameroon.

J. Djokam

Univeristy of Bamenda, Cameroon.

S. Temgoua

Deido District Hospital, Cameroon.

Djam C. Alain

Faculty of Medecine and Pharmaceutical Sciences, University of Dschang, Hospital Practionner, Cameroon.

Kedy Magamba

Deido District Hospital, Cameroon and Université of Douala, Cameroon.

*Author to whom correspondence should be addressed.


Abstract

Background: Surgical site infection (SSI) is defined as infections occurring within 30 days after a surgical operation, or within one year if an implant is left in place after the procedure. Surgical site infection is classified by the american center for disease control (CDC) into superficial incisional surgical site infections SSI, deep incisional SSI and organ/space SSI.

Objectives: The objectives of this study were to determine the prevalence of post-surgical site infections, assess the risk factors, determine the various and most microorganisms encountered and study the antibiotic sensitivity in post-surgical site infection after post-surgical site infection in Deido district hospital Douala.

Materials and Methods: we conducted a 3 months hospital based prospective study on general surgery, obstetric and gynecologic records admission at the Deido district Hospital Douala from February 1st 2020 to April 30th 2020. We included available files of the general surgery, obstetrics and gynecology. We excluded paediatrics and medical. The study was approved by the institutional ethic review board of the faculty of health sciences of the university of Bamenda.

Results: We had 133 of post-surgical patients in general surgery, obstetric and gynecologic. The prevalence of post-surgical site infection was 32,3% (43/133). Male gender aged 50-60 years were more affected than female to developed SSI. Diabetes mellitus and immunodepression by the human immuno deficiency virus had respective prevalence of 48.1 and 81,8% and increased hosptal stay after operation. Peritonitis with perforation was the most involved (14%). The identified germs were Staphylococcus aureus (11,3%), followed by Escherichia coli (8%), Pseudomonas aeruginosa (3,8%) and pseudomonas spp (3%). Staphylococcus aureus was sensible to vancomycin (73,33%), netilmicin, amikacin (6o%). Escherichia coli was sensible to gentamycin, ciprofloxacin, augmentin with a prevalence of 63,64%. Pseudomonas aeruginosa was sensible to pristinacine (80%) and amikacin (60%). Pseudomonas spp was sensible to netilmicin, amikacin (75%) followed by gentamicin, levofloxacin and ofloxacin (50%).

Conclusion: The prevalence of Post-surgical site infection was high,  the clinical spectrum and bacterial  sensitivity was diverse.

Keywords: Surgical site infection, Deido district hospital, bacterial profile


How to Cite

Tsatedem , Faustin Atemkeng, Fondop J., Bayol A. D., J. H. Donfack, J. Djokam, S. Temgoua, Djam C. Alain, and Kedy Magamba. 2023. “Bacteriological Profile of Surgical Site Infection: A Descriptive Study at Deido District Hospital in Douala, Cameroon”. Advances in Research 24 (6):30-38. https://doi.org/10.9734/air/2023/v24i6981.

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References

Owens CD, Stoessel K. Surgical site infections: Epidemiology, microbiology and prevention. J Hosp Infect. 2008;70Suppl; 2:3-10.

Cooney CM Triclosan comes under scrutiny. Environ Heath Perspect 2010; 118: 242.

VanEk B, Bakker FP, van Dulken H, Dijkmans BA Infections after craniotomy: A retrospective study. J Infect 1986;12:105-109.

Kluytmans J Surgical infections including burns. In: Wenzel R (Ed.) Prevention and control of nosocomial infections (3rd Edn). Baltimore: Williams & Wilkins. 1997;841-865.

Paocharoen V, Mingmalairak C, Apisarnthanarak A Comparison of surgical wound infection after preoperative skin preparation with 4% chlorhexidine [correction of chlohexidine] and povidone iodine: A prospective randomized trial. J Med Assoc Thai 2009;92:898-902. .

Marco F, Vallez R, Gonzalez P, Ortega L, de la Lama J, et al. Study of the efficacy of coated Vicryl plus antibacterial suture in an animal model of orthopedic surgery. Surg Infect (Larchmt). 2007;8:359-365.

Chua RA, Lim SK, Chee CF, Chin SP, Kiew LV, Sim KS, Tay ST. Surgical site infection and development of antimicrobial sutures: A review. European Review for Medical & Pharmacological Sciences. 2022;26(3).

White AJ, Fiani B, Jarrah R, Momin AA, Rasouli J. Surgical site infection prophylaxis and wound management in spine surgery. Asian Spine Journal. 2022;16(3):451.

AL-Aali K. Evaluation of surveillance for surgical site infections and drug susceptibility patterns, Taif, Saudi Arabia. Ann Clin Lab Res. 2016;4:2.

Noble W. Skin as a source for hospital infection. Infect Control. 1986;7:111-112.

Leaper D, McBain AJ, Kramer A, Assadian O, Sanchez JL, et al. Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection. Ann R Coll Surg Engl. 2010; 92:453-458.

Gomez-Alonso A, Garcia-Criado FJ, Parreno-Manchado FC. Study of the efficacy of Coated VICRYL Plus Antibacterial suture (coated Polyglactin 910 suture with Triclosan) in two animal models of general surgery. J Infect 2007; 54:82-88.

Justinger C, Moussavian MR, Schlueter C, Kopp B, Kollmar O, et al. Antibacterial coating of abdominal closure sutures and wound infection. Surgery 2009;145:330-334.

Farina C, Goglio A, Conedera G, Minelli F, Caprioli A. Antimicrobial susceptibility of Escherichia coli O157 and other enterohaemorrhagic Escherichia coli isolated in Italy. Eur J Clin Microbiol Infect Dis 1996;15:351-353.

Nichols RL. Preventing surgical site infections: A surgeon's perspective. Emerg Infect Dis 2001;7 :220-224.

National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004;32:470-485.

Rothenburger S, Spangler D, Bhende S, Burkley D. In Vitro Antimicrobial Evaluation of Coated VICRYL* Plus Antibacterial Suture (Coated Polyglactin 910 with Triclosan) using Zone of Inhibition Assays. Surg Infect (Larchmt). 2002;1;79- 87.

World Health Organization (2009) WHO Guidelines for Safe Surgery; 2009.

Available:http://whqlibdoc.who.int/publications/2009/9789241598552_ eng.pdf.

DeLissovoy G, Fraeman K, Hutchins V, Murphy D, Song D, et al. Surgical site infection: incidence and impact on hospital utilization and treatment costs. Am J Infect Control 2009; 37: 387-397.

Pinto FM, de Souza RQ, da Silva CB, Mimica LM, Graziano KU. Analysis of the microbial load in instruments used in orthopedic surgeries. Am J Infect Control 2010 ;38: 229-233.

Howard RJ, Lee JT Surgical wound infections: epidemiology, surveillance, and clinical management. Allyn& Bacon. East Norwalk, CT; 1995.

Kagansky N, Berner Y, Koren-Morag N, Perelman L, Knobler H, et al. Poor nutritional habits are predictors of poor outcome in very old hospitalized patients. Am J Clin Nutr 2005;82:784-791.

Clotilde Njall et al. Ecologie bactérienne de l’infection nosocomiale au service de réanimation de l’hôpital Laquintinie de Douala, Cameroun. Pan African Medical Journal. 2013;14:140.

DOI : 10.11604/pamj.2013.14.140.1818].

Korol E, Johnston K, Waser N, et al. A systematic review of risk factors associated with surgical site infections among surgical patients. Plos One 2013;8:e83743.

Gibbons C, Bruce J, Carpenter J, et al. Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection. Health Technol Assess. 2011; 15:1–156.

Kanwalpreet Kaur, Loveena Oberoi, Pushpa Devi. Bacteriological profile of surgical site infections. IAIM. 2017;4(12): 77- 83.