Cytological Assessment of Vaginal Epithelial Cells in Undergraduate Females of Reproductive Age in Ogun State, South-West Nigeria

Adepoju Paul Olusegun *

Department of Medical Laboratory Science, School of Public and Allied Health, Babcock University, Ogun State, Nigeria.

Solaja Anuoluwani Adeola

Department of Medical Laboratory Science, School of Public and Allied Health, Babcock University, Ogun State, Nigeria.

Adediji Isaac

Department of Medical Laboratory Science, School of Public and Allied Health, Babcock University, Ogun State, Nigeria.

Nabofa Williams

Physiology Department, Ben Carson School of Medicine, Babcock University, Ogun State, Nigeria.

Adepoju Victoria Feyikemi

Department of Reproductive Health, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

This study assessed the vaginal epithelial cells and its relationship with the reproductive hormones as a determinant for fertility. 100 students participated in this cross-sectional study. The established approach to the evaluation of ovarian function and endocrine disorders in the woman is based on serial biochemical analyses of hormones, such as estrogen, progesterone, luteinizing hormones and their metabolites. This study analyzed the ratio of parabasal, intermediate and superficial cells in comparison with the presenting hormones. The biochemical analyses can be effectively supplemented by the old-fashioned endometrial biopsies, or studies of endocervical mucus. In addition, the vaginal smear may sometimes provide useful information and has the advantage of being easy to obtain, rapidly evaluated, and inexpensive. Cytology is the study of cells collected by various means through microscopic examination. In the case of humans, the cytologic approach is particularly valuable if laboratories specializing in endocrine analysis are not readily available. The principle of the cytologic hormonal analysis is simple. The degree of maturation of the squamous epithelium of the female genital tract depends on steroid hormones, mainly estrogen. Various factors contribute to the fertility status of a woman. In the case of this study, age, abortion and use of contraceptives are the significant contributing factors (p <0.05, t >1.96).

Keywords: Vaginal maturation index (VMI), infertility, vaginal smear, cytology


How to Cite

Olusegun, Adepoju Paul, Solaja Anuoluwani Adeola, Adediji Isaac, Nabofa Williams, and Adepoju Victoria Feyikemi. 2020. “Cytological Assessment of Vaginal Epithelial Cells in Undergraduate Females of Reproductive Age in Ogun State, South-West Nigeria”. Advances in Research 21 (10):46-53. https://doi.org/10.9734/air/2020/v21i1030251.

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