Synthesis, Characterization and Antibacterial Assay of Some Schiff Base Metal (II) Complexes
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Published
May 19, 2020
Page:
28-34
Main Article Content
Auwalu Uba
Department of Weights and Measures, Federal Ministry of Industry, Trade and Investment, Nigeria.
Misbahu Muhammad Ladan
Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.
Usman Abubakar Adamu
Department of Chemistry, Gombe State University, Gombe, Nigeria.
Buhari Magaji
Department of Chemistry, Gombe State University, Gombe, Nigeria.
Muhammad Nazifi Ibrahim
Department of Chemistry, Gombe State University, Gombe, Nigeria.
Mukhtar Muhammad Sani
Department of Chemistry, Gombe State University, Gombe, Nigeria.
Abstract
The complexes of Co (II), Mn (II) and Ni (II) with Schiff base derived from pentane-2, 4-dione and 2-aminobenzoic acid were synthesized and characterized by molar conductivity, magnetic susceptibility, Infrared and elemental analyses. The solubility test on the Schiff base and its metal (II) complexes revealed their solubility in most organic solvents except chloroform and diethyl ether. The molar conductivity of the complexes was small indicating that they are non-electrolytes. The antibacterial susceptibility test conducted on the Schiff base and the metal (II) complexes showed a good activity except Ni (II) complex.
Keywords:
Antibacterial susceptibility, non-electrolytes, magnetic susceptibility, molar conductivity, schiff base ligands.
Article Details
How to Cite
Uba, A., Ladan, M. M., Adamu, U. A., Magaji, B., Ibrahim, M. N., & Sani, M. M. (2020). Synthesis, Characterization and Antibacterial Assay of Some Schiff Base Metal (II) Complexes. Advances in Research, 21(5), 28-34. https://doi.org/10.9734/air/2020/v21i530204
Section
Original Research Article
References
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Mustapha AN, Ndahi NP, Paul BB, Fugu MB. Synthesis characterization and antimicrobial studies of metal (II) complexes of ciprofloxacin. Journal of Chemical and Pharmaceutical Research. 2014;6(4):588-593.
Bycong – Goo J, Chac- Pyong, Hee-Nam C, Ki- Hyung C, Yohng- Kook C. Synthesis and characterisation of schiff base derived from 2-hydroxyl-1 -naphthaldehyde and aliphatic diamines. Korean Chem. Soc. 1996;17(8):687-693.
Adamu UA, Buhari Magaji, Ibrahim MN, Sani MM. Synthesis, characterization and antibacterial evaluation of Mn (II), Co (II) and Cu (II) complexes of schiff base derived from 3-aminophenol and benzaldehyde. Asian Journal of Chemical Science. 2020;7(2):39-44.
Geary WJ. The use of conductivity measurements in organic solvents for the characterization of coordination compounds. Coordination Chemical Review. 1971;7:81-122.
Mohammed GG, Omar MM, Hindy AM. Metal complexes of schiff base: Preparation, characterization and biological activity. Turkey Journal of Chem. 2006;30(3):361-382.
Gary LM, Donald AT. Inorganic chemistry. 4th ed., Dan Kaveney, United States of America. 2011;321.
Ashraf MA, Mahmoud KA, Maah MJ, Yosoff I. International Conference on Chemistry and Chemical Process ICPCBEE. Singapore. 2011;10:1-7.
El-ajaily M, Maihub A, Etorki A, Ben-Saber S, Elmajani M. Coordination behavior of phenolic and benzylic hydroxyl groups in complexation of their schiff base s with Zn(II) and Cd (II) ions. Journal of Pharm. Biomed Sci. 2013;28(28):695-697.
El-ajaily MM, Alassbaly FS, Etorki AM, Maihub AA. Mixed-ligand chelate formation of Co(II), Ni(II), Cu(II) and Zn(II) ions with schiff base as main ligand and amino acid as co-ligand international research. Journal of Pure & Applied Chemistry. 2015;5(3): 229-237.
Aliyu HN, Ado I. Studies of Mn(II) and Nickel(II) complexes with schiff base derived from 2-aminobenzoic acid and salisaldehyde. Journal of Biochemistry. 2011;23(1):9-16.
Hossein J, Jelas H, Mohd HSI, Roshana-Rafiee M, Afsah-Hejri L, Abdollahi Y, Rezayi M, Vafaei N. Well diffusion method for evaluation of antibacteria. Activity of Copper Phenyl Fatty Hydroxamate Synthesized from Canola & Palm Kernel Oils. Digest Journal of Nanomaterials & Biostructure. 2013;8(3):1263-1270.
Bycong-Goo J, Chac- Pyong Hee-Nam C, Ki- Hyung C, Yohng- Kook C. Synthesis and characterization of schiff base derived from 2-hydroxyl-1-naphthaldehyde and aliphatic diamines. Korean Chem. Soc. 1996;17(8):687-693.
Mustapha AN, Ndahi NP, Paul BB, Fugu MB. Synthesis characterization and antimicrobial studies of metal (II) complexes of ciprofloxacin. Journal of Chemical and Pharmaceutical Research. 2014;6(4):588-593.
Bycong – Goo J, Chac- Pyong, Hee-Nam C, Ki- Hyung C, Yohng- Kook C. Synthesis and characterisation of schiff base derived from 2-hydroxyl-1 -naphthaldehyde and aliphatic diamines. Korean Chem. Soc. 1996;17(8):687-693.
Adamu UA, Buhari Magaji, Ibrahim MN, Sani MM. Synthesis, characterization and antibacterial evaluation of Mn (II), Co (II) and Cu (II) complexes of schiff base derived from 3-aminophenol and benzaldehyde. Asian Journal of Chemical Science. 2020;7(2):39-44.
Geary WJ. The use of conductivity measurements in organic solvents for the characterization of coordination compounds. Coordination Chemical Review. 1971;7:81-122.